CANet has over 97,000 patients enrolled in cardiac research programs and more than 200 investigators across Canada. Our Network conducts clinical research under three broad themes.
Research from our Network has a significant impact on health and wealth creation in Canada.
We provide the biotechnology industry with opportunities to develop, test, and market new technologies and therapies for the diagnosis and treatment of cardiac arrhythmias. With our digital health initiatives, we capitalize on advances in computing power, internet-based communication, and accessible data to improve cardiac arrhythmia-related knowledge and care.
Our research partners include clinicians, biomedical and other researchers, engineers, industry and government, and most importantly, patients.
From governance to research to cardiac disease management, patients are co-leaders in our Network.
We value and ensure patient partnership, their involvement, and their acceptance of research methodologies throughout the research cycle; from its conception to execution, from its implementation to evaluation. Their participation enriches research outcomes, allows patients to co-manage their cardiac arrhythmia disorders, and helps produce economic and social benefits for Canada.
There is an unprecedented opportunity to evaluate the impact of patient involvement on Network operations and outcomes. In doing so, we are adding to the growing science on patient engagement and providing evidence for future public policy development in healthcare delivery and innovation.
To learn more about our patient partners’ involvement, click here.
as of March 2024
Project Title | Project Lead(s) | Project Track | CANet Funds | Matching Funds |
STRATEGIC RESEARCH GRANT | ||||
Assessment of Norepinephrine Transport Inhibition to Prevent Recurrent Vasovagal Syncope (POST6) | Robert Sheldon, Satish Raj | Syncope | $249,929.00 | $292,739.00 |
Canadian Syncope Risk Score - Optimal Management of Low-Risk Syncope Patients (CSRS) | Venkatesh Thirguanasambandamoorthy | Syncope | $730,344.00 | $1,478,698.00 |
Remote Patient Management for Cardiac Implantable Electronic Devices (RPM-CIED) | Ratika Parkash | Sudden Cardiac Death | $231,200.00 | $614,843.00 |
Atrial Image-guided Decision to Optimize Treatment of Atrial Fibrillation (AID-AF) | Allan Skanes , Frank Prato | Atrial Fibrillation | $496,200.00 | $1,054,300.00 |
Early Invasive vs. Delayed Intervention for Atrial Fibrillation (EARLY-AF) | Jason Andrade | Atrial Fibrillation | $450,062.00 | $1,667,000.00 |
The Canadian Genetic Heart Rhythm (CGHR) Network: Innovative Strategies to Reduce the Risk of Sudden Cardiac Death Using Novel Clinical and Population Approaches | Andrew Krahn , Robert Hamilton | Sudden Cardiac Death | $249,165.00 | $355,000.00 |
Reducing Sudden Cardiac Death via ICT: Coordinated Use of Information and Communication Technologies (ICT) to Empower Patients and their Families to Reduce Sudden Cardiac Death Post Myocardial Infarction | Calum Redpath | Sudden Cardiac Death | $210,000.00 | $235,000.00 |
Patient-Centered AF Management Program (PCAF) | Peter Leong-Sit , Ben Glover | Atrial Fibrillation | $171,903.00 | $220,000.00 |
Community Alternatives for Syncope Management in the Emergency Room (CASMER) | Satish Raj | Syncope | $1,389,476.00 | $563,166.00 |
Acute Myocardial Infarction Quality Assurance Study Canada (AMIQA) | Jaimie Manlucu , Stephen Wilton , Stephanie Frisbee | Sudden Cardiac Death | $342,549.00 | $385,500.00 |
Decreasing Hospital Admissions from the Emergency Department for Acute Atrial Fibrillation | Ian Stiell , Debra Eagles | Atrial Fibrillation | $169,774.00 | $60,000.00 |
Targeted Initiatives to Decrease the Burden of Sudden Cardiac Death in Canada – A CANet-CanROC Collaboration | Paul Dorian , Steven Lin | Sudden Cardiac Death | $1,246,941.00 | $14,452,260.00 |
The Canadian Syncope Atlas (CANSync): A Tool for Surveillance, Patient Engagement and Monitoring | Roopinder Sandhu , Padma Kaul | Syncope | $329,996.00 | $99,998.00 |
REMO-SYNC - Optimal Management of Low-Risk Syncope Patients — Phase 2 | Venkatesh Thiruganasambandamoorthy | Syncope | $748,152.00 | $1,675,481.00 |
VANISH 2 | John Sapp | Sudden Cardiac Death | $523,540.00 | $2,689,677.00 |
Improving the Care and Survival for Prehospital SCD Victims via Transformative Changes to 9-1-1 Ambulance Communication –Assisted CPR Instructions and the Development of Innovative Technology: A CANet-CanROC-Industry Partnership | Christian Vaillancourt | Sudden Cardiac Death | $999,641.00 | $4,440,419.00 |
Decreasing Hospital Admissions from the Emergency Department for Acute Atrial Fibrillation — Phase 2 | Ian Stiell | Atrial Fibrillation | $778,616.00 | $1,536,000.00 |
Remote Patient Management for Cardiac Implantable Electronic Devices (RPM-CIED) — Phase 2 | Ratika Parkash | Sudden Cardiac Death | $1,209,573.00 | $3,182,836.00 |
MAJOR INDUSTRY-PARTNERED RESEARCH GRANT | ||||
Risk Estimation Following Infarction Noninvasive Evaluation - ICD efficacy (REFINE ICD) | Derek Exner | Sudden Cardiac Death | $2,575,000.00 | $10,300,000.00 |
Resynchronization for Ambulatory Heart Failure Trial – LV Endocardial Approach (RAFT-LVendo) | Jaimie Manlucu | Sudden Cardiac Death | $600,000.00 | $1,915,839.00 |
FOCUSED INVESTMENT PROGRAM / SOCIAL SCIENCES GRANT | ||||
Building Collaboration for a Sustainable Future | Cheryl Mitchell , Pam Ramsay | Atrial Fibrillation, Syncope, Sudden Cardiac Death | $45,000.00 | $- |
Mapping the Patient Journey | Mary Runte , Mark Speechly , Fiona Clement | $240,000.00 | $- | |
Predictors of Perceived Self-Efficacy and Empowerment in Patients at Increased Risk of Sudden Unexpected Cardiac Arrest and their Caregivers | Colette Seifer | Sudden Cardiac Death | $109,978.00 | $- |
COMMERCIALIZATION GRANT | ||||
Catheter Contact-Force Controller for Cardiac Ablation Therapy | Daniel Gelman , Maria Drangova | Atrial Fibrillation | $300,000.00 | $445,000.00 |
Catheter-Based Imaging Tools for Characterization of Myocardial Ablation Lesions | Brian Courtney | Atrial Fibrillation | $300,000.00 | $360,000.00 |
Project Babelfish: A Transcutaneous Physiologic Sensor for Home and Clinical Use | Robert Sheldon | Syncope | $300,000.00 | $- |
An Autoimmune Biomarker for Arrhythmogenic Right Ventricular Cardiomyopathy | Robert Hamilton | Sudden Cardiac Death | $150,000.00 | $- |
AED on the Fly Program - An AED Drone Delivery Feasibility Study | Sheldon Cheskes | Sudden Cardiac Death | $150,000.00 | $- |
SEED GRANT | ||||
Development of Predictive Tests and Procedures for Risk Assessment of Sudden Death in Epilepsy | Robert Dumaine | Sudden Cardiac Death | $25,000.00 | $- |
Determining Processes of Care Associated with Improved Survival in Atrial Fibrillation Patients in Ontario, Canada | Sheldon Singh | Atrial Fibrillation | $25,000.00 | $- |
Simplified Home and Ambulatory Monitoring in Patients Evaluated for Inherited Arrhythmia (SHAPE - IA) | Andrew Krahn | Sudden Cardiac Death | $25,000.00 | $- |
Catheter Ablation for Atrial Fibrillation: Impact on Physical Activity, Quality of Life, and Burden of Arrhythmia | Benedict Glover | Atrial Fibrillation | $25,000.00 | $50,000.00 |
IGNITE GRANT | ||||
Computer Simulated Atrial Fibrillation Tool to Reduce Hospitalizations and Emergency Department Visits | Ratika Parkash | Atrial Fibrillation | $25,000.00 | $25,000.00 |
CHAT DISCOVERY GRANT | ||||
Catheter Contact-Force Control During Cardiac Ablation Therapy: In Vivo Evaluation | Daniel Gelman | Atrial Fibrillation | $25,000.00 | $375,000.00 |
Big Data Analytics in Large AF Patient Databases: Correlates to Hospitalizations and ED Visits | Jiro Inoue | Atrial Fibrillation | $10,000.00 | $- |
SURFACE (in SUppoRt oF Ablation CandidatEs) | Katherine Allan | Atrial Fibrillation | $10,000.00 | $31,500.00 |
Dilated Cardiomyopathy with Ataxia: Zebrafish as a Model to Understand the Pathophysiology of Sudden Cardiac Death | Saman Rezazadeh | Sudden Cardiac Death | $15,000.00 | $- |
The Effect of Frailty Assessment on Anticoagulation Rates in Elderly with Nonvalvular Atrial Fibrillation (UNFRAIL AF) | Zardasht Oqab | Atrial Fibrillation | $15,000.00 | $- |
Standard versus Intensive Monitoring Post-Myocardial Infarction Looking for New-Onset Atrial Fibrillation (SIMPL-AF) and Predictors of Poor Outcomes (SIMPL-PPO) | Christopher Cheung | Atrial Fibrillation | $25,000.00 | $50,000.00 |
Redefining Electrical Storm Based on Clinical Outcomes: Data from the RAFT Trial | Ihab Elsokkari | Sudden Cardiac Death | $10,000.00 | |
The Effects of HIIT on Time to Recurrence of Atrial Fibrillation After Electro – Cardioversion in Patients with Persistent Atrial Fibrillation: A Randomized Controlled Pilot Feasibility Trial | Lisa Cotie | Atrial Fibrillation | $15,000.00 | $- |
Trends in Clinical Outcomes After Out-of-Hospital Cardiac Arrest Due to Ischemic Heart Disease | Nigel Tan | Sudden Cardiac Death | $15,000.00 | $10,000.00 |
Switching Off Cardiac Resynchronization Therapy in Non-Responders to Present Ventricular Arrhythmias and Related Hospitalizations: A Pilot Randomized Clinical Trial | Bishoy Deif | Sudden Cardiac Death | $15,000.00 | $- |
Auto-Antibodies in Brugada Syndrome: Validation and Assessment of a Novel Disease Marker | Meena Fatah | Sudden Cardiac Death | $25,000.00 | $- |
Left Atrial Function and Fibrosis After Successful Catheter Ablation for AF: A Pilot Study | Daniel Ramirez | Atrial Fibrillation | $15,000.00 | $- |
POST-DOCTORAL FELLOWSHIP PROGRAM | ||||
Investigating the Role of the Vectorcardiographically Derived QRS Area in CRT Response | Elien Engels | Other | $45,000.00 | $45,000.00 |
Real-Time Localization of Ventricular Tachycardia Origin from the 12-Lead ECG | Shijie Zhou | Sudden Cardiac Death | $45,000.00 | $45,000.00 |
CLINICAL FELLOWSHIP PROGRAM | ||||
Incidence Rate, Cardiac Symptoms, Circumstances, Triggers and Health Care Encounters Preceding Sudden Cardiac Death Caused by Hypertrphic Cardiomyopathy | Adaya Weissler-Snir | Sudden Cardiac Death | $60,000.00 | $60,000.00 |
Structural, Functional and Autonomic Imaging of the Atrium in AF - Start Imaging AF | Stephen Duffet | Atrial Fibrillation | $60,000.00 | $60,000.00 |
Decreasing Emergency Room Visits in Patients with Atrial Fibrillation Using the Digital Healthcare Platform of VIRTUES | Andrea Lee | Atrial Fibrillation | $60,000.00 | $60,000.00 |
Dilated Cardiomyopathy with Ataxia: How can a Mitochondrial Transport Protein Mutation Result in Sudden Cardiac Death? | Saman Rezazadeh | Sudden Cardiac Death | $60,000.00 | $60,000.00 |
IMPLEMENTATION GRANT | ||||
Ventricular Tachycardia Alation Versus Escalated Antiarrhythmic Drug Therapy in Ischemic Heart Disease (VANISH) | John Sapp | Sudden Cardiac Death | $162,000.00 | $- |
Optimal Management of Low-Risk Syncope Patients | Venkatesh Thirguanasambandamoorthy | Syncope | $336,618.00 | $- |