Episode 19: The good, the bad, and the ugly: Exploring the Science of Cholesterol with Dr. Rob Hegele

In this episode of Ticker Talk, host Ann-Marie Julien speaks with Dr. Rob Hegele, distinguished Professor of Medicine and Biochemistry at Western University and Director of the London Regional Genomics Centre at Robarts Research Institute. Dr. Hegele also cares for over 2400 patients in his Lipid Clinic at University Hospital in London, Ontario. His research investigates the human genome to identify DNA markers that may suggest a hereditary predisposition to certain diseases. In doing so, this allows for preventative and personalized treatment strategies aimed at improving patients’ overall health outcomes.

This episode speaks to the role of lipids, particularly cholesterol and triglycerides, and their impact on cardiovascular health. Dr. Hegele explains the mechanisms behind LDL and HDL cholesterol, touches upon the lesser-known lipoprotein a (Lp(a)) and apolipoprotein b (ApoB) and emphasizes the importance of both primary and secondary prevention of heart disease. He brings listeners on a deep dive into the world of cholesterol management using concrete examples with a dash of light-hearted wit.

Dr. Hegele’s insights into cholesterol and lipid management offer hope for individuals dealing with cardiovascular concerns. As research continues to evolve, the prevention and management of heart disease is becoming increasingly personalized and effective, ensuring a healthier future for patients worldwide.

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